ISA Interchange Control Header Segment: Updated Guide for 2025

Introduction

The Interchange Control Header (ISA) segment is a critical component of the EDI X12 standard, serving as the envelope that initiates and identifies an interchange of one or more functional groups and interchange-related control segments. Accurate configuration of the ISA segment ensures seamless communication between trading partners and compliance with industry standards.

ISA Segment Overview

The ISA segment is a fixed-length record consisting of 16 data elements, each with specific formatting requirements. Below is a detailed breakdown of each element:

ElementSizeNameDescriptionNotes
ISA012Authorization Information Qualifier00Indicates no authorization information present.
ISA0210Authorization InformationTen spacesBlank if ISA01 is ’00’.
ISA032Security Information Qualifier00Indicates no security information present.
ISA0410Security InformationTen spacesBlank if ISA03 is ’00’.
ISA052Interchange ID Qualifier (Sender)ZZMutually defined; commonly used for custom identifiers.
ISA0615Interchange Sender IDSender’s unique IDLeft-justified and space-filled.
ISA072Interchange ID Qualifier (Receiver)ZZMutually defined; commonly used for custom identifiers.
ISA0815Interchange Receiver IDReceiver’s unique IDLeft-justified and space-filled.
ISA096Interchange DateYYMMDDDate of the interchange.
ISA104Interchange TimeHHMMTime of the interchange.
ISA111Repetition Separator^Must be unique and not used elsewhere in the segment.
ISA125Interchange Control Version Number00501Indicates the version of the EDI standard.
ISA139Interchange Control NumberUnique numberMust match the control number in the IEA segment.
ISA141Acknowledgment Requested0 or 1‘1’ indicates acknowledgment requested.
ISA151Usage IndicatorP or T‘P’ for production data; ‘T’ for test data.
ISA161Component Element Separator:Must be unique and not used elsewhere in the segment.

Best Practices for ISA Segment Configuration

  • Unique Identifiers: Ensure that both the sender and receiver IDs (ISA06 and ISA08) are unique and agreed upon by trading partners.
  • Control Numbers: Maintain sequential control numbers in ISA13 to track interchanges effectively.
  • Delimiters: Choose delimiters (ISA11 and ISA16) that do not conflict with data content.
  • Testing: Use ‘T’ in ISA15 during testing phases and switch to ‘P’ for production environments.

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