Botox (J0585) HCPCS Code: 2026 Medicare Units & Wastage Rules

Last Updated: September 12, 2026

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Billing J0585 for Botox (onabotulinumtoxinA) requires careful attention to Medicare's Medical Necessity rules to differentiate between covered medical procedures (like chronic migraines) and non-covered cosmetic use.

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Billing Units for Botox (J0585)

The HCPCS definition for J0585 is "Injection, onabotulinumtoxinA, 1 unit".

Botox is supplied in 100-unit or 200-unit single-use vials. You must bill the exact number of units administered to the patient.

DrugCodeAdministered DosageBilling Units
Botox (onabotulinumtoxinA)J0585155 units155

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Medical Necessity & ICD-10 Codes

To establish Medical Necessity, you must link J0585 to a covered diagnosis. Common Medicare-approved indications include:

  • G43.709 - Chronic migraine without aura, not intractable, without status migrainosus
  • G24.3 - Spasmodic torticollis (Cervical dystonia)
  • N31.9 - Neuromuscular dysfunction of bladder, unspecified

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Discarded Drug (JW Modifier)

Because Botox vials are single-use, any unused portion must be discarded and billed properly. If a 200-unit vial is opened but only 155 units are administered, you must bill:

  • Line 1: J0585 (155 units)
  • Line 2: J0585-JW (45 units)

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