Eylea (J0178) HCPCS Code: 2026 RT/LT Modifiers & Units

Last Updated: September 12, 2026

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Eylea (aflibercept) is billed under J0178 for intravitreal injections. Ophthalmology clinics frequently face denials due to missing laterality modifiers (RT/LT) or incorrect unit counts.

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Unit Calculation for Eylea (J0178)

The HCPCS code J0178 is defined as "Injection, aflibercept, 1 mg".

The standard dose per eye is 2 mg. If administering to one eye, bill 2 units. If administering bilaterally (both eyes), bill 4 units.

DrugCodeAdministered DosageBilling Units
EyleaJ01782 mg (One Eye)2

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Crucial: Modifiers RT, LT, and 50

Medicare requires you to specify which eye was injected. You must append Modifier RT (Right eye) or LT (Left eye) to the surgical administration code (67028). If treating both eyes, follow your specific MAC's guidelines on using Modifier 50 vs separate RT/LT lines.

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Administration Edits

Bill CPT 67028 (Intravitreal injection of a pharmacologic agent). Ensure your NCCI edit checks are clear if billing a concurrent eye exam (e.g., 92012 or 99213).

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