Kyprolis (J9047) HCPCS Code: 2026 Oncology Billing & Units

Last Updated: September 12, 2026

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Kyprolis (carfilzomib) is billed under J9047 for the treatment of multiple myeloma. Oncology billers must master the 1mg unit calculations and JW wastage rules to ensure prompt reimbursement.

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Unit Calculation for Kyprolis (J9047)

The HCPCS code J9047 is defined as "Injection, carfilzomib, 1 mg".

If administering a 60 mg dose, you will bill exactly 60 units.

DrugCodeAdministered DosageBilling Units
KyprolisJ904760 mg60

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Medical Necessity & Wastage

The primary covered diagnosis is Multiple Myeloma (C90.00). Furthermore, because Kyprolis comes in single-dose vials, you must append Modifier JW for any discarded portion of the vial, or JZ if the entire vial was used.

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Administration Edits

Bill CPT 96413 for chemotherapy IV infusion. Check your NCCI edits if billing concurrent E/M visits.

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