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Soliris (J1300) HCPCS Code: 2026 Medicare Units & IV Rules

Last Updated: September 12, 2026

Soliris (eculizumab) is an ultra-orphan drug billed under J1300 ↗. Given its extreme cost, a single billing error will result in a massive financial delay for your practice.

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Billing Units for Soliris (J1300)

The HCPCS definition for J1300 ↗ is "Injection, eculizumab, 10 mg".

For a standard 900 mg maintenance dose, divide by 10. You must bill exactly 90 units.

DrugCodeAdministered DosageBilling Units
SolirisJ1300900 mg90

Medical Necessity & ICD-10 Codes

Verify Medical Necessity

Don't risk a denial. See if your ICD-10 code is on the approved Medicare LCD list.

Medicare rigorously restricts Soliris to specific rare conditions:

Administration Coding

Soliris is administered intravenously. Bill standard therapeutic infusion codes (96365 ↗ for the initial hour).

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